Description
Zopiclone (7.5 mg) is a sleeping medication used for the short-term treatment of serious sleep disorders or insomnia. It is a non-benzodiazepine hypnotic medicine and is commonly known as a ‘Z-drug’. It is made to help those struggling with sleep-related problems, including difficulty falling asleep, interrupted sleep, and frequent awakenings during the night. It works by influencing the brain’s relaxing neurotransmitter, gamma-aminobutyric acid (GABA). Zopiclone 7.5mg comes in the form of pills. It is also available in a liquid for those who find it difficult to swallow tablets, but your doctor will need to order it specifically. This medication is only available via prescription. When sleeplessness becomes severe and starts hampering individual daily life, mood and complete health, this medicine is usually recommended by the medical professional. This medicine works by slowing down activity in the brain, which makes it simpler for the body to fall asleep. This medicine is typically given under medical guidance in the United Kingdom (UK), and it should be used with caution and only when suggested by a skilled medical professional to guarantee safe and appropriate treatment.
Summary of Zopiclone
| Type of drug | non-benzodiazepine hypnotics sleeping pill |
| Health conditions prescribed for | Sleep problems such as insomnia as a short term treatment (NHS, 2022) |
| Active ingredient | Zopiclone |
| Brand names | There are various branded variations of Zopiclone such as Imovane and Zimovane (Drugs.com, 2023). |
| Available strengths | 7.5mg |
| Available as | Tablet, oral liquid |
| Possible side effects | Sleepiness, tiredness, and a metallic taste in your mouth |
| Patient Information Leaflet | For more information on the medication please refer to the patient information leaflet for Zopiclone. |
How Zopiclone Works
Zopiclone works by binding to GABA (gamma-aminobutyric acid) receptors in the brain. GABA is a neurotransmitter that inhibits nerve activity and promotes calm. Zopiclone reduces central nervous system activity by boosting the actions of GABA, resulting in a relaxing effect. This process will minimise the time and help you fall asleep by improving the time duration of sleeping. Also, it helps you stay asleep by making it less likely that you will wake up often during the night. The complete effects are more stable, and the overall effect is a more stable and constant sleep pattern. To reduce the risks of negative effects, it is crucial to use this medication sensibly and only under a doctor’s supervision.
Key Benefits of Zopiclone (7.5mg)
The following are the benefits of Zopiclone (7.5 mg):
- It makes you go to sleep more quickly.
- It lessens awakenings at night.
- It increases the length of sleep.
- It works well for temporary sleeplessness.
- It enhances the general quality of sleep.
Who Can Use Zopiclone (7.5mg)
The doctor recommends zopiclone (7.5 mg) as a short-term treatment for adult insomnia, lasting 7 to 14 days. Adults who have trouble sleeping are treated with it, including the following:
- having trouble falling asleep
- Awaken during the night
- Getting up too early
- Severe or disruptive sleep disorders brought on by emotional or mental health problems.
This medicine is not recommended for long-term treatment, i.e., more than 4 weeks or 1 month, in the treatment of chronic insomnia. It could lead to tolerance and dependence, which could induce withdrawal and rebound sleeplessness if you stop using it suddenly. Long-term use is usually considered an “off-label” or unapproved use of the medicine.
Usage of Zopiclone (7.5mg)
Zopiclone 7.5 mg is normally prescribed once a day before going to bed, and it is only recommended when the individual is going to sleep for at least 7 to 8 hours or for the whole night. Waking earlier may result in various side effects, which include drowsiness or reduced alertness for the next day. This is a short-term medication that is typically used for 2 to 4 weeks, with a tapering period if necessary. Using this medicine for long periods can lead to serious negative effects, and it also reduces effectiveness over time.
Intake of alcohol is highly restricted while taking this treatment, as it can increase the chance of sedative effects and various side effects. Kindly follow the medical professional suggestion when you are going through this treatment.
Who Should Avoid Zopiclone
You should avoid using Zopiclone if:
- Allergic or hypersensitive to zopiclone or any of the other substances in your medication.
- Rash, difficulty swallowing or breathing, and swelling of the lips, face, throat, or tongue are all signs of an allergic reaction.
- Condition that causes significant muscle weakening.
- Lungs do not function properly.
- Sleep apnoea is a condition in which you stop breathing for brief periods of time during the night.
- Serious liver issues.
- Under the age of 18, Zopiclone’s safety and efficacy for children have yet to be established.
- Ever experienced sleepwalking or other strange activity while partially awake after taking zopiclone.
Safety and Side Effects
Most side effects don’t need medical treatment and go away when your body gets used to the medicine. If they don’t go away or if you’re worried about them, talk to your doctor.
Common side effects
- A dry mouth or a metallic or bitter taste in your mouth
- Feeling tired (next day)
Serious side effects
- Amnesia
- Hallucinations
- Fall over (above 65 years of age)
- Delusions
- Depression
- Allergic reaction
Rare but serious effects:
- Anaphylaxis
- Behavioural or mood changes
If the advice on how to cope does not help and a side effect persists or worsens, consult a medical professional.
Zopiclone vs Other Sleeping Tablets
Zopiclone is part of a series of medicines called Z-drugs. People often compare it to other sleeping medications like nitrazepam and eszopiclone. They all help those who can’t sleep, but they work and have different effects.
- Nitrazepam is a benzodiazepine that works for a longer time. It may be more effective than Z-drugs, but it could also cause more sedation the next day and a higher chance of dependence.
- Eszopiclone is quite similar to zopiclone; however, it is a more refined form with similar effects on sleep initiation and maintenance.
- Zopiclone has a quick start of action and is extensively used in the UK to treat short-term insomnia. It may be less likely than typical benzodiazepines to cause sustained sedation. Individual sleep patterns and medical advice are used to determine medication selection.
Sleep Hygiene Tips
The sleep hygiene tips are given as follows:
- Medicines like zopiclone are helpful in improving the sleeping hygiene, which can increase the effectiveness of medications.
- Making proper sleeping timing, early to bed and waking up early at the same time daily, is very beneficial in maintaining the human body’s internal clock.
- Strictly avoiding the caffeine, nicotine, and heavy food in the evening meal or dinner may decrease sleeping issues.
- Better sleep can also be promoted by limiting screen time before bed and setting up a peaceful, quiet, and dark sleeping space.
- Include relaxing methods in your daily routine before going to bed, which include reading books, meditation and deep breathing exercises, which are very helpful for improving sleep quality.
- As per various scientific research, lifestyle modification or adjustments with medication are highly recommended for good results in insomnia treatment.
FAQs
Q1: How quickly is zopiclone effective?
The zopiclone shows its effectiveness within 30 to 60 minutes after consumption of medication. Therefore, it is advised to take it right before bed.
Q2: Is it possible to take Zopiclone every night?
Zopiclone is made for short-term use only. This medication should be taken in the same way as suggested by a medical professional and not used continuously without medical guidance.
Q3: Can one become addicted to zopiclone?
If you use Zopiclone for a long time or in higher doses than your doctor says, it can become addictive. That’s why it’s usually only used for a short time.
Q4: What makes zopiclone taste bitter?
Zopiclone frequently causes a metallic or bitter taste as a side effect. It can last for a short while after taking the medication and is caused by the way the substance is metabolized.
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Author & Medical Reviewer
Written by:
Dr. Ritika Joshi, MSc, PhD
Medical Content Writer
Disclaimer
This content is for informational purposes only and does not constitute medical advice. Zopiclone is a prescription-only medicine in the UK and should only be used under the supervision of a qualified healthcare professional. Always consult your GP or pharmacist before starting any treatment.
References:
- NHS. About Zopiclone, February 18, 2022
- Zopiclone: a sleeping pill used to treat bouts of insomnia [Internet]. nhs.uk. 2021 [cited 18 October 2021]. Available from: https://www.nhs.uk/medicines/zopiclone/
- BNF – Zopiclone
- Drugs.com – Zopiclone
- Controlled drugs in social care homes – Care Quality Commission
- Schedules of Controlled Substances: Placement of Zopiclone Into Schedule IV
- MedSafe – New Zealand Medicines and Medical Devices Safety Authority. Imovane Product Label
- MedSafe – New Zealand Medicines and Medical Devices Safety Authority. Zopiclone Actavis Product Label
- Hemmeter U, Müller M, Bischof R, Annen B, Holsboer-Trachsler E. Effect of zopiclone and temazepam on sleep EEG parameters, psychomotor and memory functions in healthy elderly volunteers. Psychopharmacology (Berl) 2000;147:384-96.
- Wadworth AN, McTavish D. Zopiclone: A review of its pharmacological properties and therapeutic efficacy as an hypnotic. Drugs Aging 1993;3:441-59.
- Allain H, Bentué-Ferrer D, Tarral A, Gandon J-M. Effects on postural oscillation and memory functions of a single dose of zolpidem 5 mg, zopiclone 3.75 mg and lormetazepam 1 mg in elderly healthy subjects. A randomized, cross-over, double-blind study versus placebo. Eur J Clin Pharmacol 2003;59:179-88.






mywebadmins@proton.me –
Zopiclone 7.5 mg works quickly and helps in getting deep, uninterrupted sleep. It usually starts working within an hour and improves sleep quality significantly. Mild side effects like a bitter taste or slight morning drowsiness can occur. Overall, very effective for short-term insomnia.